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YAC tripeptide of epidermal growth factor promotes the proliferation of HaCaT keratinocytes through activation of EGFR

Epidermal growth factor (EGF) is known to play key roles in skin regeneration and wound-healing. Here, we demonstrate that Pep2-YAC, a tripeptide covering residues 29-31 in the B loop of EGF, promotes the proliferation of HaCaT keratinocytes with activity comparable to EGF. The treatment of HaCaT ce...

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Detalles Bibliográficos
Autores principales: Yoo, Yeon Ho, Kim, Yu Ri, Kim, Min Seo, Lee, Kyoung-Jin, Park, Kyeong Han, Hahn, Jang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261517/
https://www.ncbi.nlm.nih.gov/pubmed/25179402
http://dx.doi.org/10.5483/BMBRep.2014.47.10.151