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Modeling T cell receptor recognition of CD1-lipid and MR1-metabolite complexes
BACKGROUND: T cell receptors (TCRs) can recognize diverse lipid and metabolite antigens presented by MHC-like molecules CD1 and MR1, and the molecular basis of many of these interactions has not been determined. Here we applied our protein docking algorithm TCRFlexDock, previously developed to perfo...
Autores principales: | Pierce, Brian G, Vreven, Thom, Weng, Zhiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261541/ https://www.ncbi.nlm.nih.gov/pubmed/25260513 http://dx.doi.org/10.1186/1471-2105-15-319 |
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