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Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection

BACKGROUND: Previously, we demonstrated that unlike subcutaneous or intramuscular vaccination, intranasal vaccination of BALB/c mice with whole Leishmania amazonensis antigens leads to protection against cutaneous leishmaniasis. Here, the role of parasite serine proteases in the protective immunity...

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Detalles Bibliográficos
Autores principales: de Matos Guedes, Herbert Leonel, da Silva Costa, Beatriz Lilian, Chaves, Suzana Passos, de Oliveira Gomes, Daniel Cláudio, Nosanchuk, Joshua Daniel, De Simone, Salvatore Giovanni, Rossi-Bergmann, Bartira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261548/
https://www.ncbi.nlm.nih.gov/pubmed/25239157
http://dx.doi.org/10.1186/1756-3305-7-448

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