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Differential sleep-promoting effects of dual orexin receptor antagonists and GABA(A) receptor modulators

BACKGROUND: The current standard of care for insomnia includes gamma-aminobutyric acid receptor A (GABA(A)) activators, which promote sleep as well as general central nervous system depression. Dual orexin receptor antagonists (DORAs) represent an alternative mechanism for insomnia treatment that in...

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Detalles Bibliográficos
Autores principales:	Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261741/ https://www.ncbi.nlm.nih.gov/pubmed/25242351 http://dx.doi.org/10.1186/1471-2202-15-109

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