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Automated Selection of Hotspots (ASH): enhanced automated segmentation and adaptive step finding for Ki67 hotspot detection in adrenal cortical cancer
BACKGROUND: In prognosis and therapeutics of adrenal cortical carcinoma (ACC), the selection of the most active areas in proliferative rate (hotspots) within a slide and objective quantification of immunohistochemical Ki67 Labelling Index (LI) are of critical importance. In addition to intratumoral...
Autores principales: | Lu, Hao, Papathomas, Thomas G, van Zessen, David, Palli, Ivo, de Krijger, Ronald R, van der Spek, Peter J, Dinjens, Winand NM, Stubbs, Andrew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261753/ https://www.ncbi.nlm.nih.gov/pubmed/25421287 http://dx.doi.org/10.1186/s13000-014-0216-6 |
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