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Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes

INTRODUCTION: Osteoarthritis (OA) is a whole joint disease, and characterized by progressive degradation of articular cartilage, synovial hyperplasia, bone remodeling and angiogenesis in various joint tissues. Exosomes are a type of microvesicles (MVs) that may play a role in tissue-tissue and cell-...

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Detalles Bibliográficos
Autores principales:	Kato, Tomohiro, Miyaki, Shigeru, Ishitobi, Hiroyuki, Nakamura, Yoshihiro, Nakasa, Tomoyuki, Lotz, Martin K, Ochi, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261911/ https://www.ncbi.nlm.nih.gov/pubmed/25092378 http://dx.doi.org/10.1186/ar4679

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