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Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2

Indoleamine 2,3-dioxygenases (IDOs) are tryptophan-catabolizing enzymes with immunomodulatory functions. However, the biological role of IDO2 and its relationship with IDO1 are unknown. To assess the relationship between IDO2 and IDO1, we investigated the effects of co-expression of human (h) IDO2 o...

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Detalles Bibliográficos
Autores principales:	Lee, Young-Kwan, Lee, Hoon Bok, Shin, Dong-Mi, Kang, Min Jueng, Yi, Eugene C, Noh, Seungjoo, Lee, Jaewoo, Lee, Chulbom, Min, Chang-Ki, Choi, Eun Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261913/ https://www.ncbi.nlm.nih.gov/pubmed/25394548 http://dx.doi.org/10.1038/emm.2014.69

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