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Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren’s syndrome

INTRODUCTION: Dendritic cells (DC) are the most potent antigen-presenting cells of the immune system, involved in both initiating immune responses and maintaining tolerance. Dysfunctional and via toll-like receptor (TLR) ligands activated DC have been implicated in the development of autoimmune dise...

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Detalles Bibliográficos
Autores principales: Vogelsang, Petra, Karlsen, Marie, Brun, Johan G, Jonsson, Roland, Appel, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261979/
https://www.ncbi.nlm.nih.gov/pubmed/25113744
http://dx.doi.org/10.1186/ar4682