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Efficient Targeting of Fatty-Acid Modified Oligonucleotides to Live Cell Membranes through Stepwise Assembly

[Image: see text] Lipid modifications provide efficient targeting of oligonucleotides to live cell membranes in a range of applications. Targeting efficiency is a function of the rate of lipid DNA insertion into the cell surface and its persistence over time. Here we show that increasing lipid hydro...

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Detalles Bibliográficos
Autores principales: Weber, Robert J., Liang, Samantha I., Selden, Nicholas S., Desai, Tejal A., Gartner, Zev J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261982/
https://www.ncbi.nlm.nih.gov/pubmed/25325667
http://dx.doi.org/10.1021/bm501467h