In-Line Separation by Capillary Electrophoresis Prior to Analysis by Top-Down Mass Spectrometry Enables Sensitive Characterization of Protein Complexes

[Image: see text] Intact protein analysis via top-down mass spectrometry (MS) provides a bird’s eye view over the protein complexes and complex protein mixtures with the unique capability of characterizing protein variants, splice isoforms, and combinatorial post-translational modifications (PTMs)....

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Detalles Bibliográficos
Autores principales: Han, Xuemei, Wang, Yueju, Aslanian, Aaron, Fonslow, Bryan, Graczyk, Beth, Davis, Trisha N., Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262260/
https://www.ncbi.nlm.nih.gov/pubmed/25382489
http://dx.doi.org/10.1021/pr500971h

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