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Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins
BACKGROUND: Vaccines against avian influenza viruses often require high hemagglutinin (HA) doses or adjuvants to achieve serological titers associated with protection against disease. In particular, viruses of the H7 subtype frequently do not induce strong antibody responses following immunization....
Autores principales: | Blanchfield, Kristy, Kamal, Ram P, Tzeng, Wen-Pin, Music, Nedzad, Wilson, Jason R, Stevens, James, Lipatov, Aleksander S, Katz, Jacqueline M, York, Ian A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262278/ https://www.ncbi.nlm.nih.gov/pubmed/25213778 http://dx.doi.org/10.1111/irv.12285 |
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