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Giant Lysosomes as a Chemotherapy Resistance Mechanism in Hepatocellular Carcinoma Cells
Despite continuous improvements in therapeutic protocols, cancer-related mortality is still one of the main problems facing public health. The main cause of treatment failure is multi-drug resistance (MDR: simultaneous insensitivity to different anti-cancer agents), the underlying molecular and biol...
Autores principales: | Colombo, Federico, Trombetta, Elena, Cetrangolo, Paola, Maggioni, Marco, Razini, Paola, De Santis, Francesca, Torrente, Yvan, Prati, Daniele, Torresani, Erminio, Porretti, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262459/ https://www.ncbi.nlm.nih.gov/pubmed/25493932 http://dx.doi.org/10.1371/journal.pone.0114787 |
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