Upregulated periostin promotes angiogenesis in keloids through activation of the ERK 1/2 and focal adhesion kinase pathways, as well as the upregulated expression of VEGF and angiopoietin-1

Periostin, a secreted extracellular matrix protein, is highly expressed in wound healing and in various types of human cancer and is involved in angiogenesis. Keloids, considered dermal benign tumors, are granulomatous lesions characterized by capillary proliferation. However, the underlying regulat...

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Detalles Bibliográficos
Autores principales: ZHANG, ZHE, NIE, FANGFEI, CHEN, XINLEI, QIN, ZELIAN, KANG, CHUNFU, CHEN, BIN, MA, JIANXUN, PAN, BOLIN, MA, YONGGUANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262479/
https://www.ncbi.nlm.nih.gov/pubmed/25369801
http://dx.doi.org/10.3892/mmr.2014.2827

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