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Effects of thyroxine and donepezil on hippocampal acetylcholine content, acetylcholinesterase activity, synaptotagmin-1 and SNAP-25 expression in hypothyroid adult rats

A growing number of studies have revealed that neurocognitive impairment, induced by adult-onset hypothyroidism, may not be fully restored by traditional hormone substitution therapies, including thyroxine (T4). The present study has investigated the effect of T4 and donepezil (DON; an acetylcholine...

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Detalles Bibliográficos
Autores principales:	WANG, FEN, ZENG, XIANZHONG, ZHU, YANGBO, NING, DAN, LIU, JUNXIA, LIU, CHUNLEI, JIA, XUEMEI, ZHU, DEFA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262484/ https://www.ncbi.nlm.nih.gov/pubmed/25371181 http://dx.doi.org/10.3892/mmr.2014.2825

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