Cargando…

Effects of thyroxine and donepezil on hippocampal acetylcholine content, acetylcholinesterase activity, synaptotagmin-1 and SNAP-25 expression in hypothyroid adult rats

A growing number of studies have revealed that neurocognitive impairment, induced by adult-onset hypothyroidism, may not be fully restored by traditional hormone substitution therapies, including thyroxine (T4). The present study has investigated the effect of T4 and donepezil (DON; an acetylcholine...

Descripción completa

Detalles Bibliográficos
Autores principales:	WANG, FEN, ZENG, XIANZHONG, ZHU, YANGBO, NING, DAN, LIU, JUNXIA, LIU, CHUNLEI, JIA, XUEMEI, ZHU, DEFA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262484/ https://www.ncbi.nlm.nih.gov/pubmed/25371181 http://dx.doi.org/10.3892/mmr.2014.2825

Ejemplares similares

Effects of thyroxin and donepezil on hippocampal acetylcholine content and syntaxin-1 and munc-18 expression in adult rats with hypothyroidism
por: WANG, NAN, et al.
Publicado: (2014)

Concurrent administration of thyroxine and donepezil induces plastic changes in the prefrontal cortex of adult hypothyroid rats
por: Wang, Fen, et al.
Publicado: (2017)

Diverse Effects of an Acetylcholinesterase Inhibitor, Donepezil, on Hippocampal Neuronal Death after Pilocarpine-Induced Seizure
por: Jeong, Jeong Hyun, et al.
Publicado: (2017)

Efficacy and Safety of Once-Weekly Thyroxine for Thyroxine-Resistant Hypothyroidism
por: Jayakumari, Chellama, et al.
Publicado: (2019)

The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents
por: Shin, Chang Yell, et al.
Publicado: (2018)

The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition
por: Rants’o, Thankhoe A., et al.
Publicado: (2022)

Evaluation of the Optimal Thyroxine Levels for Thyroxine Hormone Replacement in Patients With Central Hypothyroidism
por: Lee, Ka Fai, et al.
Publicado: (2021)

Thyroxine and treatment of hypothyroidism: seven decades of experience
por: Mateo, Roselyn Cristelle I., et al.
Publicado: (2019)

Effect of Donepezil, Tacrine, Galantamine and Rivastigmine on Acetylcholinesterase Inhibition in Dugesia tigrina
por: Bezerra da Silva, Cristiane, et al.
Publicado: (2016)

Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23
por: Weber, Jens P., et al.
Publicado: (2014)

Relation of Gut Microbes and L-Thyroxine Through Altered Thyroxine Metabolism in Subclinical Hypothyroidism Subjects
por: Yao, Zhenyu, et al.
Publicado: (2020)

Dyslipidemia in subclinical hypothyroidism and the effect of thyroxine on lipid profile
por: Asranna, Ajay, et al.
Publicado: (2012)

Acute mania after thyroxin supplementation in hypothyroid state
por: Verma, Rohit, et al.
Publicado: (2013)

Isoflurane-Induced Spatial Memory Impairment in Mice is Prevented by the Acetylcholinesterase Inhibitor Donepezil
por: Su, Diansan, et al.
Publicado: (2011)

Metal based donepezil analogues designed to inhibit human acetylcholinesterase for Alzheimer’s disease
por: Junaid, Md., et al.
Publicado: (2019)

Basal Serum Thyroxine Level should Guide Initial Thyroxine Replacement Dose in Neonates with Congenital Hypothyroidism
por: Günbey, Ceren, et al.
Publicado: (2021)

Effect of thyroxine on munc-18 and syntaxin-1 expression in dorsal hippocampus of adult-onset hypothyroid rats
por: Zhu, Y., et al.
Publicado: (2012)

Distribution of Intravenously Administered Acetylcholinesterase Inhibitor and Acetylcholinesterase Activity in the Adrenal Gland: (11)C-Donepezil PET Study in the Normal Rat
por: Watabe, Tadashi, et al.
Publicado: (2014)

Acetylcholinesterase and Nicotinic Acetylcholine Receptors in Schistosomes and Other Parasitic Helminths
por: You, Hong, et al.
Publicado: (2017)

The Effects of L-thyroxine Treatment on QT Dispersion in Primary Hypothyroidism
por: Kweon, Kyoung Hee, et al.
Publicado: (2007)

Homocysteine and Fibrinogen Changes with L-thyroxine in Subclinical Hypothyroid Patients
por: Çakal, Başak, et al.
Publicado: (2007)

Abstract 27: Neuropathy in primary hypothyroidism and response to thyroxine replacement
por: Muthukrishnan, J, et al.
Publicado: (2022)

Evaluation of Reproductive Outcome in Infertile Hypothyroid Women on Thyroxine Therapy
por: Wadhwa, Leena, et al.
Publicado: (2020)

Free triiodothyronine/free thyroxine ratio in children with congenital hypothyroidism
por: Sydlik, Carmen, et al.
Publicado: (2022)

Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors
por: Ismail, Mohamed M., et al.
Publicado: (2012)

Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration in Normal Human Subjects: A (11)C-donepezil PET Study
por: Mochida, Ikuko, et al.
Publicado: (2017)

The Effect of L-Thyroxine Treatment on Hypothyroid Symptom Scores and Lipid Profile in Children with Subclinical Hypothyroidism
por: Çatlı, Gönül, et al.
Publicado: (2014)

Endothelial Functioning and Hemodynamic Parameters in Rats with Subclinical Hypothyroid and the Effects of Thyroxine Replacement
por: Gao, Cuixia, et al.
Publicado: (2015)

Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues
por: Caliandro, Rosanna, et al.
Publicado: (2018)

Donepezil prevents RANK-induced bone loss via inhibition of osteoclast differentiation by downregulating acetylcholinesterase
por: Sato, Tsuyoshi, et al.
Publicado: (2015)

Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle
por: Redman, Robert R., et al.
Publicado: (2022)

Pregnancy outcomes with thyroxine replacement for subclinical hypothyroidism: Role of thyroid autoimmunity
por: Jayaraman, Muthukrishnan, et al.
Publicado: (2013)

Renal dysfunction manifesting in subclinical hypothyroidism—a possible role for thyroxine
por: Asim, Muhammad, et al.
Publicado: (2010)

Weight and Body Mass Index for Predicting Thyroxine Dose in Primary Hypothyroidism
por: Raashid, Kashif, et al.
Publicado: (2021)

Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism
por: Pantalone, Kevin M., et al.
Publicado: (2015)

Efficacy and Safety of Once Weekly Thyroxine as Compared to Daily Thyroxine in Managing Primary Hypothyroidism: A Systematic Review and Meta-Analysis
por: Dutta, Deep, et al.
Publicado: (2021)

On Some Structural Analogies between Acetylcholinesterase and the Macromolecular Receptor of Acetylcholine
por: Changeux, Jean-Pierre, et al.
Publicado: (1969)

Postoperative Administration of the Acetylcholinesterase Inhibitor, Donepezil, Interferes with Bone Healing and Implant Osseointegration in a Rat Model
por: Al-Hamed, Faez Saleh, et al.
Publicado: (2020)

Evaluation of the Adverse Effects of Chronic Exposure to Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and Biochemical Assessments
por: Audira, Gilbert, et al.
Publicado: (2020)

A curious case of refractory hypothyroidism due to selective malabsorption of oral thyroxine
por: Damle, Nishikant, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ouetofqiiif1qu9il503je3t02