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Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: What have we learned to date?

Research into the mechanisms by which proteins fold into their native structures has been on-going since the work of Anfinsen in the 1960s. Since that time, the folding mechanisms of small, water-soluble proteins have been well characterised. By contrast, progress in understanding the biogenesis and...

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Detalles Bibliográficos
Autores principales: McMorran, Lindsay M., Brockwell, David J., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262575/
https://www.ncbi.nlm.nih.gov/pubmed/24613287
http://dx.doi.org/10.1016/j.abb.2014.02.011