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A load driver device for engineering modularity in biological networks
The behavior of gene modules in complex synthetic circuits is often unpredictable(1–4). Upon joining modules to create a circuit, downstream elements (such as binding sites for a regulatory protein) apply a load to upstream modules that can negatively affect circuit function(1,5). Here we devise a g...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262674/ https://www.ncbi.nlm.nih.gov/pubmed/25419739 http://dx.doi.org/10.1038/nbt.3044 |