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Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis
BACKGROUND: A fundamental challenge for cancer therapy is that each tumor contains a highly heterogeneous cell population whose structure and mechanistic underpinnings remain incompletely understood. Recent advances in single-cell gene expression profiling have created new possibilities to character...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262970/ https://www.ncbi.nlm.nih.gov/pubmed/25517911 http://dx.doi.org/10.1186/s13059-014-0525-9 |