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Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia
BACKGROUND: Schizophrenia is a severe neuropsychiatric disorder that is hypothesized to result from disturbances in early brain development. There is mounting evidence to support a role for developmentally regulated epigenetic variation in the molecular etiology of the disorder. Here, we describe a...
Autores principales: | Pidsley, Ruth, Viana, Joana, Hannon, Eilis, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Mechawar, Naguib, Turecki, Gustavo, Schalkwyk, Leonard C, Bray, Nicholas J, Mill, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262979/ https://www.ncbi.nlm.nih.gov/pubmed/25347937 http://dx.doi.org/10.1186/s13059-014-0483-2 |
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