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Activation of c-Src tyrosine kinase mediated the degradation of occludin in ventilator-induced lung injury
BACKGROUND: Ventilator-induced lung injury (VILI) is characterized by increased alveolar permeability, pulmonary edema. The tyrosine kinase, c-Src, is involved in VILI but its role has not been fully elucidated. This study examined the relationship between c-Src activation and occludin levels in VIL...
Autores principales: | Zhao, Tao, Liu, Mengjie, Gu, Changping, Wang, Xin, Wang, Yuelan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262993/ https://www.ncbi.nlm.nih.gov/pubmed/25471013 http://dx.doi.org/10.1186/s12931-014-0158-2 |
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