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Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal

BACKGROUND: The aim of this study was to analyse the reasons for not starting or for early of radiotherapy at the Radiation Oncology Department. METHODS: All radiotherapy treatments from March 2010 to February 2012 were included. Early withdrawals from treatment those that never started recorded. Cl...

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Autores principales: Arenas, Meritxell, Sabater, Sebastià, Gascón, Marina, Henríquez, Ivan, Bueno, M José, Rius, Àngels, Rovirosa, Àngels, Gómez, David, Lafuerza, Anna, Biete, Albert, Colomer, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263009/
https://www.ncbi.nlm.nih.gov/pubmed/25472662
http://dx.doi.org/10.1186/s13014-014-0260-0
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author Arenas, Meritxell
Sabater, Sebastià
Gascón, Marina
Henríquez, Ivan
Bueno, M José
Rius, Àngels
Rovirosa, Àngels
Gómez, David
Lafuerza, Anna
Biete, Albert
Colomer, Jordi
author_facet Arenas, Meritxell
Sabater, Sebastià
Gascón, Marina
Henríquez, Ivan
Bueno, M José
Rius, Àngels
Rovirosa, Àngels
Gómez, David
Lafuerza, Anna
Biete, Albert
Colomer, Jordi
author_sort Arenas, Meritxell
collection PubMed
description BACKGROUND: The aim of this study was to analyse the reasons for not starting or for early of radiotherapy at the Radiation Oncology Department. METHODS: All radiotherapy treatments from March 2010 to February 2012 were included. Early withdrawals from treatment those that never started recorded. Clinical, demographic and dosimetric variables were also noted. RESULTS: From a total of 3250 patients treated and reviewed, 121 (4%) did not start or complete the planned treatment. Of those, 63 (52%) did not receive any radiotherapy fraction and 58 (48%) did not complete the course, 74% were male and 26% were female. The mean age was 67 ± 13 years. The most common primary tumour was lung (28%), followed by rectum (16%). The aim of treatment was 62% radical and 38% palliative, 44% of patients had metastases; the most common metastatic site was bone, followed by brain. In 38% of cases (46 patients) radiotherapy was administered concomitantly with chemotherapy (10 cases (22%) were rectal cancers). The most common reason for not beginning or for early withdrawal of treatment was clinical progression (58/121, 48%). Of those, 43% died (52/121), 35 of them because of the progression of the disease and 17 from other causes. Incomplete treatment regimens were due to toxicity (12/121 (10%), of which 10 patients underwent concomitant chemotherapy for rectal cancer). CONCLUSIONS: The number of patients who did not complete their course of treatment is low, which shows good judgement in indications and patient selection. The most common reason for incomplete treatments was clinical progression. Rectal cancer treated with concomitant chemotherapy was the most frequent reason of the interruption of radiotherapy for toxicity.
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spelling pubmed-42630092014-12-12 Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal Arenas, Meritxell Sabater, Sebastià Gascón, Marina Henríquez, Ivan Bueno, M José Rius, Àngels Rovirosa, Àngels Gómez, David Lafuerza, Anna Biete, Albert Colomer, Jordi Radiat Oncol Research BACKGROUND: The aim of this study was to analyse the reasons for not starting or for early of radiotherapy at the Radiation Oncology Department. METHODS: All radiotherapy treatments from March 2010 to February 2012 were included. Early withdrawals from treatment those that never started recorded. Clinical, demographic and dosimetric variables were also noted. RESULTS: From a total of 3250 patients treated and reviewed, 121 (4%) did not start or complete the planned treatment. Of those, 63 (52%) did not receive any radiotherapy fraction and 58 (48%) did not complete the course, 74% were male and 26% were female. The mean age was 67 ± 13 years. The most common primary tumour was lung (28%), followed by rectum (16%). The aim of treatment was 62% radical and 38% palliative, 44% of patients had metastases; the most common metastatic site was bone, followed by brain. In 38% of cases (46 patients) radiotherapy was administered concomitantly with chemotherapy (10 cases (22%) were rectal cancers). The most common reason for not beginning or for early withdrawal of treatment was clinical progression (58/121, 48%). Of those, 43% died (52/121), 35 of them because of the progression of the disease and 17 from other causes. Incomplete treatment regimens were due to toxicity (12/121 (10%), of which 10 patients underwent concomitant chemotherapy for rectal cancer). CONCLUSIONS: The number of patients who did not complete their course of treatment is low, which shows good judgement in indications and patient selection. The most common reason for incomplete treatments was clinical progression. Rectal cancer treated with concomitant chemotherapy was the most frequent reason of the interruption of radiotherapy for toxicity. BioMed Central 2014-12-04 /pmc/articles/PMC4263009/ /pubmed/25472662 http://dx.doi.org/10.1186/s13014-014-0260-0 Text en © Arenas et al.; licensee BioMed Central Ltd. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Arenas, Meritxell
Sabater, Sebastià
Gascón, Marina
Henríquez, Ivan
Bueno, M José
Rius, Àngels
Rovirosa, Àngels
Gómez, David
Lafuerza, Anna
Biete, Albert
Colomer, Jordi
Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title_full Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title_fullStr Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title_full_unstemmed Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title_short Quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
title_sort quality assurance in radiotherapy: analysis of the causes of not starting or early radiotherapy withdrawal
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263009/
https://www.ncbi.nlm.nih.gov/pubmed/25472662
http://dx.doi.org/10.1186/s13014-014-0260-0
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