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Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity

BACKGROUND: In approximately 10% of newly diagnosed individuals in Europe, HIV-1 variants harboring transmitted drug resistance mutations (TDRM) are detected. For some TDRM it has been shown that they revert to wild type while other mutations persist in the absence of therapy. To understand the mech...

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Detalles Bibliográficos
Autores principales:	Pingen, Marieke, Wensing, Annemarie MJ, Fransen, Katrien, De Bel, Annelies, de Jong, Dorien, Hoepelman, Andy IM, Magiorkinis, Emmanouil, Paraskevis, Dimitrios, Lunar, Maja M, Poljak, Mario, Nijhuis, Monique, Boucher, Charles AB
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263067/ https://www.ncbi.nlm.nih.gov/pubmed/25575025 http://dx.doi.org/10.1186/s12977-014-0105-9

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