Cargando…

HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia

3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are widely used for secondary stroke prevention. Besides their lipid-lowering activity, pleiotropic effects on neuronal survival, angiogenesis, and neurogenesis have been described. In view of these observations, we were interested...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kilic, Ertugrul, Reitmeir, Raluca, Kilic, Ülkan, Caglayan, Ahmet Burak, Beker, Mustafa Caglar, Kelestemur, Taha, Ethemoglu, Muhsine Sinem, Ozturk, Gurkan, Hermann, Dirk M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263103/ https://www.ncbi.nlm.nih.gov/pubmed/25565957 http://dx.doi.org/10.3389/fncel.2014.00422

Ejemplares similares

Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation
por: Beker, Mustafa C., et al.
Publicado: (2015)

Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice
por: Kilic, Ulkan, et al.
Publicado: (2017)

Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
por: Beker, Mustafa C., et al.
Publicado: (2019)

Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
por: KILIÇ, Ertuğrul, et al.
Publicado: (2020)

Acute and Post-acute Neuromodulation Induces Stroke Recovery by Promoting Survival Signaling, Neurogenesis, and Pyramidal Tract Plasticity
por: Caglayan, Ahmet B., et al.
Publicado: (2019)

The therapeutic role of minocycline in Parkinson’s disease
por: Cankaya, Seyda, et al.
Publicado: (2019)

Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors
por: Samizo, Shigeyoshi, et al.
Publicado: (2023)

Pleiotropic effects of the HMG-CoA reductase inhibitors
por: Mihos, Christos G, et al.
Publicado: (2011)

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?
por: Gonzalez-Jimenez, Irene, et al.
Publicado: (2021)

The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation
por: Gelosa, Paolo, et al.
Publicado: (2007)

Positive pleiotropic effects of HMG-CoA reductase inhibitor on vitiligo
por: Noël, Martin, et al.
Publicado: (2004)

Structural and functional characterization of HMG-COA reductase from Artemisia annua
por: Kiran, Usha, et al.
Publicado: (2010)

Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2014)

Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism
por: Han, Ki Hoon
Publicado: (2018)

Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
por: Lorenzo-Villalba, Noel, et al.
Publicado: (2021)

Eupatilin Alleviates Hyperlipidemia in Mice by Inhibiting HMG-CoA Reductase
por: Kim, Kyung-Joo, et al.
Publicado: (2023)

Minocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy
por: Yulug, Burak, et al.
Publicado: (2020)

Evidence that osteogenic and neurogenic differentiation capability of epidural adipose tissue-derived stem cells was more pronounced than in subcutaneous cells
por: SOLMAZ, Bilgehan, et al.
Publicado: (2020)

Microanatomical study of pyramidal neurons in the contralesional somatosensory cortex after experimental ischemic stroke
por: Merino-Serrais, Paula, et al.
Publicado: (2022)

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
por: Friesen, Jon A, et al.
Publicado: (2004)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase
por: Würtz, Peter, et al.
Publicado: (2016)

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
por: Schumacher, Marc M, et al.
Publicado: (2015)

Dose-dependent neuroprotective effect of enoxaparin on cold-induced traumatic brain injury
por: Keskin, Ilknur, et al.
Publicado: (2017)

Two boron-containing compounds affect the cellular viability of SH-SY5Y cells in an in vitro amyloid-beta toxicity model
por: OZANSOY, Mehmet, et al.
Publicado: (2020)

Degradation of HMG-CoA reductase-induced membranes in the fission yeast, Schizosaccharomyces pombe
Publicado: (1995)

Role of HMG-CoA reductase inhibitors with curative radiotherapy in men with prostate cancer
por: Solanki, Abhishek A, et al.
Publicado: (2011)

Lepidopteran HMG-CoA reductase is a potential selective target for pest control
por: Li, Yuan-mei, et al.
Publicado: (2017)

HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival
por: Lacher, Sonja M, et al.
Publicado: (2017)

An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia
por: Gesto, Diana S., et al.
Publicado: (2020)

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
por: Kettunen, Johannes, et al.
Publicado: (2019)

Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor
por: Bose, Sucharita, et al.
Publicado: (2023)

Modulation of Dendritic Cell Immunobiology via Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) Reductase
por: Leuenberger, Tina, et al.
Publicado: (2014)

HMG CoA reductase inhibitors (statins) to treat Epstein–Barr virus-driven lymphoma
por: Cohen, J I
Publicado: (2005)

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast
Publicado: (1994)

Association between Use of HMG CoA Reductase Inhibitors and Mortality in HIV-Infected Patients
por: Moore, Richard D., et al.
Publicado: (2011)

Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer
por: Borgquist, Signe, et al.
Publicado: (2008)

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase
por: Dhingra, Dinesh, et al.
Publicado: (2014)

Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system
por: Tsai, Yien Che, et al.
Publicado: (2012)

Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors
por: Umeda, Ryohei, et al.
Publicado: (2019)

Development of Clinical Data Mart of HMG-CoA Reductase Inhibitor for Varied Clinical Research
por: Kim, Hun-Sung, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_43mqejmmgpfgatnmulg09r56t2