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Vesicular Stomatitis Virus Polymerase's Strong Affinity to Its Template Suggests Exotic Transcription Models

Vesicular stomatitis virus (VSV) is the prototype for negative sense non segmented (NNS) RNA viruses which include potent human and animal pathogens such as Rabies, Ebola and measles. The polymerases of NNS RNA viruses only initiate transcription at or near the 3′ end of their genome template. We me...

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Detalles Bibliográficos
Autores principales: Tang, Xiaolin, Bendjennat, Mourad, Saffarian, Saveez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263359/
https://www.ncbi.nlm.nih.gov/pubmed/25501005
http://dx.doi.org/10.1371/journal.pcbi.1004004