Cargando…
Molecular Insights into the Dynamics of Pharmacogenetically Important N-Terminal Variants of the Human β(2)-Adrenergic Receptor
The human β(2)-adrenergic receptor (β(2)AR), a member of the G-protein coupled receptor (GPCR) family, is expressed in bronchial smooth muscle cells. Upon activation by agonists, β(2)AR causes bronchodilation and relief in asthma patients. The N-terminal polymorphism of β(2)AR at the 16(th) position...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263363/ https://www.ncbi.nlm.nih.gov/pubmed/25501358 http://dx.doi.org/10.1371/journal.pcbi.1004006 |