Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism

Maf1 was initially identified as a transcriptional repressor of RNA pol III-transcribed genes, yet little is known about its other potential target genes or its biological function. Here, we show that Maf1 is a key downstream target of PTEN that drives both its tumor suppressor and metabolic functio...

Descripción completa

Detalles Bibliográficos
Autores principales: Palian, Beth M., Rohira, Aarti D., Johnson, Sandra A. S., He, Lina, Zheng, Ni, Dubeau, Louis, Stiles, Bangyan L., Johnson, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263377/
https://www.ncbi.nlm.nih.gov/pubmed/25502566
http://dx.doi.org/10.1371/journal.pgen.1004789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263377/
https://www.ncbi.nlm.nih.gov/pubmed/25502566
http://dx.doi.org/10.1371/journal.pgen.1004789

Ejemplares similares