DNA-Protein Immunization Using Leishmania Peroxidoxin-1 Induces a Strong CD4(+) T Cell Response and Partially Protects Mice from Cutaneous Leishmaniasis: Role of Fusion Murine Granulocyte-Macrophage Colony-Stimulating Factor DNA Adjuvant

BACKGROUND: To date, no universally effective and safe vaccine has been developed for general human use. Leishmania donovani Peroxidoxin-1 (LdPxn-1) is a member of the antioxidant family of proteins and is predominantly expressed in the amastigote stage of the parasite. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Bayih, Abebe Genetu, Daifalla, Nada S., Gedamu, Lashitew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263403/
https://www.ncbi.nlm.nih.gov/pubmed/25500571
http://dx.doi.org/10.1371/journal.pntd.0003391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263403/
https://www.ncbi.nlm.nih.gov/pubmed/25500571
http://dx.doi.org/10.1371/journal.pntd.0003391

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