Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii

[Image: see text] β-Lactam resistance in Acinetobacter baumannii presents one of the greatest challenges to contemporary antimicrobial chemotherapy. Much of this resistance to cephalosporins derives from the expression of the class C β-lactamase enzymes, known as Acinetobacter-derived cephalosporina...

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Detalles Bibliográficos
Autores principales: Powers, Rachel A., Swanson, Hollister C., Taracila, Magdalena A., Florek, Nicholas W., Romagnoli, Chiara, Caselli, Emilia, Prati, Fabio, Bonomo, Robert A., Wallar, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263437/
https://www.ncbi.nlm.nih.gov/pubmed/25380506
http://dx.doi.org/10.1021/bi500887n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263437/
https://www.ncbi.nlm.nih.gov/pubmed/25380506
http://dx.doi.org/10.1021/bi500887n

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