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An astral simulacrum of the central spindle accounts for normal, spindle-less, and anucleate cytokinesis in echinoderm embryos

Cytokinesis in animal cells depends on spindle-derived spatial cues that culminate in Rho activation, and thereby actomyosin assembly, in a narrow equatorial band. Although the nature, origin, and variety of such cues have long been obscure, one component is certainly the Rho activator Ect2. Here we...

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Detalles Bibliográficos
Autores principales: Su, Kuan-Chung, Bement, William M., Petronczki, Mark, von Dassow, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263448/
https://www.ncbi.nlm.nih.gov/pubmed/25298401
http://dx.doi.org/10.1091/mbc.E14-04-0859