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Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn–plectin 1f complexes
Mutations in the cytolinker protein plectin lead to grossly distorted morphology of neuromuscular junctions (NMJs) in patients suffering from epidermolysis bullosa simplex (EBS)-muscular dystrophy (MS) with myasthenic syndrome (MyS). Here we investigated whether plectin contributes to the structural...
Autores principales: | Mihailovska, Eva, Raith, Marianne, Valencia, Rocio G., Fischer, Irmgard, Banchaabouchi, Mumna Al, Herbst, Ruth, Wiche, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263455/ https://www.ncbi.nlm.nih.gov/pubmed/25318670 http://dx.doi.org/10.1091/mbc.E14-06-1174 |
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