Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis

Mycolic acids (MAs) are α-alkyl, β-hydroxy long-chain fatty acids found in abundance in the cell envelope of the Mycobacterium tuberculosis complex (MTBC). MAs form an efficient permeability barrier, modulate host innate immune responses, and are the targets of several anti-tuberculosis drugs. Using...

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Detalles Bibliográficos
Autores principales: Portevin, Damien, Sukumar, Sudarkodi, Coscolla, Mireia, Shui, Guanghou, Li, Bowen, Guan, Xue Li, Bendt, Anne K, Young, Douglas, Gagneux, Sebastien, Wenk, Markus R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263507/
https://www.ncbi.nlm.nih.gov/pubmed/25238051
http://dx.doi.org/10.1002/mbo3.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263507/
https://www.ncbi.nlm.nih.gov/pubmed/25238051
http://dx.doi.org/10.1002/mbo3.193

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