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Protoporphyrin (PPIX) efflux by the MacAB-TolC pump in Escherichia coli

In most organisms, heme biosynthesis is strictly controlled so as to avoid heme and heme precursor accumulation, which is toxic. Escherichia coli regulates heme biosynthesis by a feedback loop involving heme-induced proteolytic cleavage of HemA, glutamyl-tRNA reductase, which is the first enzyme in...

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Detalles Bibliográficos
Autores principales:	Turlin, Evelyne, Heuck, Gesine, Simões Brandão, Maria Inês, Szili, Noémie, Mellin, J R, Lange, Norbert, Wandersman, Cécile
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263509/ https://www.ncbi.nlm.nih.gov/pubmed/25257218 http://dx.doi.org/10.1002/mbo3.203

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