Cargando…
Optical Gratings Coated with Thin Si(3)N(4) Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy
New silicon nitride coated optical gratings were tested by means of Optical Waveguide Lightmode Spectroscopy (OWLS). A thin layer of 10 nm of transparent silicon nitride was deposited on commercial optical gratings by means of sputtering. The quality of the layer was tested by x-ray photoelectron sp...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263575/ https://www.ncbi.nlm.nih.gov/pubmed/25585707 http://dx.doi.org/10.3390/bios2020114 |
Sumario: | New silicon nitride coated optical gratings were tested by means of Optical Waveguide Lightmode Spectroscopy (OWLS). A thin layer of 10 nm of transparent silicon nitride was deposited on commercial optical gratings by means of sputtering. The quality of the layer was tested by x-ray photoelectron spectroscopy and atomic force microscopy. As a proof of concept, the sensors were successfully tested with OWLS by monitoring the concentration dependence on the detection of an antibody-protein pair. The potential of the Si(3)N(4) as functional layer in a real-time biosensor opens new ways for the integration of optical waveguides with microelectronics. |
---|