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The Role of the NADPH Oxidase NOX2 in Prion Pathogenesis

Prion infections cause neurodegeneration, which often goes along with oxidative stress. However, the cellular source of reactive oxygen species (ROS) and their pathogenetic significance are unclear. Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion diseases. We found tha...

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Detalles Bibliográficos
Autores principales:	Sorce, Silvia, Nuvolone, Mario, Keller, Annika, Falsig, Jeppe, Varol, Ahmet, Schwarz, Petra, Bieri, Monika, Budka, Herbert, Aguzzi, Adriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263757/ https://www.ncbi.nlm.nih.gov/pubmed/25502554 http://dx.doi.org/10.1371/journal.ppat.1004531

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