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Identification of Small Molecule Inhibitors of Pre-mRNA Splicing

Eukaryotic pre-mRNA splicing is an essential step in gene expression for all genes that contain introns. In contrast to transcription and translation, few well characterized chemical inhibitors are available with which to dissect the splicing process, particularly in cells. Therefore, the identifica...

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Detalles Bibliográficos
Autores principales:	Pawellek, Andrea, McElroy, Stuart, Samatov, Timur, Mitchell, Lee, Woodland, Andrew, Ryder, Ursula, Gray, David, Lührmann, Reinhard, Lamond, Angus I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263873/ https://www.ncbi.nlm.nih.gov/pubmed/25281741 http://dx.doi.org/10.1074/jbc.M114.590976

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