MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma

Retinoblastoma (RB) is a children's ocular cancer caused by mutated retinoblastoma 1 (Rb1) gene on both alleles. Rb1 and other related genes could be regulated by microRNAs (miRNA) via complementarily pairing with their target sites. MicroRNA-21 (miR-21) possesses the oncogenic potential to tar...

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Detalles Bibliográficos
Autores principales: Shen, Fengmei, Mo, Meng-Hsuan, Chen, Liang, An, Shejuan, Tan, Xiaohui, Fu, Yebo, Rezaei, Katayoon, Wang, Zuoren, Zhang, Lin, Fu, Sidney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263991/
https://www.ncbi.nlm.nih.gov/pubmed/25520758
http://dx.doi.org/10.7150/jca.10456

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