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How water molecules affect the catalytic activity of hydrolases - A XANES study of the local structures of peptide deformylase

Peptide deformylase (PDF) is a prokaryotic enzyme that catalyzes the deformylation of nascent peptides generated during protein synthesis and water molecules play a key role in these hydrolases. Using X-ray absorption near edge spectroscopy (XANES) and ab initio calculations we accurately probe the...

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Detalles Bibliográficos
Autores principales:	Cui, Peixin, Wang, Yu, Chu, Wangsheng, Guo, Xiaoyun, Yang, Feifei, Yu, Meijuan, Zhao, Haifeng, Dong, Yuhui, Xie, Yaning, Gong, Weimin, Wu, Ziyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264029/ https://www.ncbi.nlm.nih.gov/pubmed/25503313 http://dx.doi.org/10.1038/srep07453

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