A miR-590/Acvr2a/Rad51b Axis Regulates DNA Damage Repair during mESC Proliferation

Embryonic stem cells (ESCs) enable rapid proliferation that also causes DNA damage. To maintain genomic stabilization during rapid proliferation, ESCs must have an efficient system to repress genotoxic stress. Here, we show that withdrawal of leukemia inhibitory factor (LIF), which maintains the sel...

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Detalles Bibliográficos
Autores principales: Liu, Qidong, Wang, Guiying, Chen, Yafang, Li, Guoping, Yang, Dandan, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264031/
https://www.ncbi.nlm.nih.gov/pubmed/25458897
http://dx.doi.org/10.1016/j.stemcr.2014.10.006

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