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GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance
BACKGROUND/OBJECTIVES: Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of very low density lipoprotein (VLDL). Recently, the incretin hormone glucagon-like peptide-1 (GLP-1) has been implicated in ameliorating dyslipidemia as...
Autores principales: | Taher, Jennifer, Baker, Christopher L., Cuizon, Carmelle, Masoudpour, Hassan, Zhang, Rianna, Farr, Sarah, Naples, Mark, Bourdon, Celine, Pausova, Zdenka, Adeli, Khosrow |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264039/ https://www.ncbi.nlm.nih.gov/pubmed/25506548 http://dx.doi.org/10.1016/j.molmet.2014.09.005 |
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