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An Expandable, Inducible Hemangioblast State Regulated by Fibroblast Growth Factor

During development, the hematopoietic and vascular lineages are thought to descend from common mesodermal progenitors called hemangioblasts. Here we identify six transcription factors, Gata2, Lmo2, Mycn, Pitx2, Sox17, and Tal1, that “trap” murine cells in a proliferative state and endow them with a...

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Detalles Bibliográficos
Autores principales: Vereide, David T., Vickerman, Vernella, Swanson, Scott A., Chu, Li-Fang, McIntosh, Brian E., Thomson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264065/
https://www.ncbi.nlm.nih.gov/pubmed/25458896
http://dx.doi.org/10.1016/j.stemcr.2014.10.003