Cargando…

Low/Negative Expression of PDGFR-α Identifies the Candidate Primary Mesenchymal Stromal Cells in Adult Human Bone Marrow

Human bone marrow (BM) contains a rare population of nonhematopoietic mesenchymal stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. However, the precise phenotypic definition of these cells in adult BM has not yet been reported. In this study, we show that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Hongzhe, Ghazanfari, Roshanak, Zacharaki, Dimitra, Ditzel, Nicholas, Isern, Joan, Ekblom, Marja, Méndez-Ferrer, Simón, Kassem, Moustapha, Scheding, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264066/ https://www.ncbi.nlm.nih.gov/pubmed/25454633 http://dx.doi.org/10.1016/j.stemcr.2014.09.018

Ejemplares similares

Human Primary Bone Marrow Mesenchymal Stromal Cells and Their in vitro Progenies Display Distinct Transcriptional Profile Signatures
por: Ghazanfari, Roshanak, et al.
Publicado: (2017)

Human Non-Hematopoietic CD271(pos)/CD140a(low/neg) Bone Marrow Stroma Cells Fulfill Stringent Stem Cell Criteria in Serial Transplantations
por: Ghazanfari, Roshanak, et al.
Publicado: (2016)

Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells
por: Li, Hongzhe, et al.
Publicado: (2020)

CD146/MCAM defines functionality of human bone marrow stromal stem cell populations
por: Harkness, Linda, et al.
Publicado: (2016)

A simple and reliable protocol for long-term culture of murine bone marrow stromal (mesenchymal) stem cells that retained their in vitro and in vivo stemness in long-term culture
por: Abdallah, Basem M., et al.
Publicado: (2019)

Identification of phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow based on single-cell RNA sequencing
por: Li, Hongzhe, et al.
Publicado: (2023)

The Bone Marrow-Derived Stromal Cells: Commitment and Regulation of Adipogenesis
por: Tencerova, Michaela, et al.
Publicado: (2016)

Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow
por: Mabuchi, Yo, et al.
Publicado: (2021)

Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells
por: Andersen, Rikke K., et al.
Publicado: (2015)

Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2019)

Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells
por: Rolandsson, Sara, et al.
Publicado: (2014)

Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells
por: Elsafadi, Mona, et al.
Publicado: (2016)

Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis
por: Jafari, Abbas, et al.
Publicado: (2017)

Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential
por: Al-Nbaheen, May, et al.
Publicado: (2012)

Identification of two distinct mesenchymal stromal cell populations in human malignant glioma
por: Svensson, Andreas, et al.
Publicado: (2016)

Human Stromal (Mesenchymal) Stem Cells: Basic Biology and Current Clinical Use for Tissue Regeneration
por: Aldahmash, Abdullah, et al.
Publicado: (2012)

Identification of a clinical signature predictive of differentiation fate of human bone marrow stromal cells
por: Kowal, Justyna Magdalena, et al.
Publicado: (2021)

Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis
por: Buhl, Eva M, et al.
Publicado: (2020)

Molecular characterisation of stromal populations derived from human embryonic stem cells: Similarities to immortalised bone marrow derived stromal stem cells
por: Harkness, Linda, et al.
Publicado: (2015)

Single‐cell high‐content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells
por: Kowal, Justyna M., et al.
Publicado: (2019)

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2019)

Insulin Signaling in Bone Marrow Adipocytes
por: Tencerova, Michaela, et al.
Publicado: (2019)

Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells
por: Tencerova, Michaela, et al.
Publicado: (2019)

Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells
por: Ali, Dalia, et al.
Publicado: (2018)

Pleiotropic effects of cancer cells’ secreted factors on human stromal (mesenchymal) stem cells
por: Al-toub, Mashael, et al.
Publicado: (2013)

PDGFRα/Sca-1 Sorted Mesenchymal Stromal Cells Reduce Liver Injury in Murine Models of Hepatic Ischemia-Reperfusion Injury
por: Owen, Andrew, et al.
Publicado: (2022)

Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2019)

Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2023)

TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1‐p38 Signaling
por: Jafari, Abbas, et al.
Publicado: (2018)

Intrapulmonary autologous transplant of bone marrow-derived mesenchymal stromal cells improves lipopolysaccharide-induced acute respiratory distress syndrome in rabbit
por: Mokhber Dezfouli, Mohammad Reza, et al.
Publicado: (2018)

PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas
por: Kartha, Vinay K., et al.
Publicado: (2016)

High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancer
por: Paulsson, Janna, et al.
Publicado: (2016)

Identification and characterization of PDGFRα(+) mesenchymal progenitors in human skeletal muscle
por: Uezumi, A, et al.
Publicado: (2014)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors
por: Al-toub, Mashael, et al.
Publicado: (2019)

Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1
por: Haider, Nida, et al.
Publicado: (2020)

Bone marrow-derived mesenchymal stromal cell: what next?
por: Borges, Fernanda T, et al.
Publicado: (2018)

Bone Marrow Mesenchymal Stromal Cells: Identification, Classification, and Differentiation
por: Gao, Qianmin, et al.
Publicado: (2022)

Editorial: Differentiation and Regulation of Bone Marrow Mesenchymal Stromal Cells
por: Zhang, Hao, et al.
Publicado: (2022)

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis
por: Murayama, Emi, et al.
Publicado: (2023)

Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells
por: Wu, Erxi, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_i4mtki35gm12ioe5100tfgl1pq