3D QSAR Studies, Pharmacophore Modeling and Virtual Screening on a Series of Steroidal Aromatase Inhibitors

Aromatase inhibitors are the most important targets in treatment of estrogen-dependent cancers. In order to search for potent steroidal aromatase inhibitors (SAIs) with lower side effects and overcome cellular resistance, comparative molecular field analysis (CoMFA) and comparative molecular similar...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Huiding, Qiu, Kaixiong, Xie, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264204/
https://www.ncbi.nlm.nih.gov/pubmed/25405729
http://dx.doi.org/10.3390/ijms151120927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264204/
https://www.ncbi.nlm.nih.gov/pubmed/25405729
http://dx.doi.org/10.3390/ijms151120927

Ejemplares similares