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Indian Council of Medical Research consensus document for the management of gastric cancer
The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India. Evaluation of a patient with newly diagnosed gastric cancer should include essential tests: A standard white light endoscopy with multiple biopsies fro...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264267/ https://www.ncbi.nlm.nih.gov/pubmed/25538398 http://dx.doi.org/10.4103/0971-5851.144970 |
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author | Shrikhande, Shailesh V. Sirohi, Bhawna Barreto, Savio G. Chacko, Raju T. Parikh, Purvish M. Pautu, Jeremy Arya, Supreeta Patil, Prachi Chilukuri, Srinivas C. Ganesh, B. Kaur, Tanvir Shukla, Deepak Rath, Goura Shankar |
author_facet | Shrikhande, Shailesh V. Sirohi, Bhawna Barreto, Savio G. Chacko, Raju T. Parikh, Purvish M. Pautu, Jeremy Arya, Supreeta Patil, Prachi Chilukuri, Srinivas C. Ganesh, B. Kaur, Tanvir Shukla, Deepak Rath, Goura Shankar |
author_sort | Shrikhande, Shailesh V. |
collection | PubMed |
description | The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India. Evaluation of a patient with newly diagnosed gastric cancer should include essential tests: A standard white light endoscopy with multiple biopsies from the tumor for confirmation of the diagnosis, a computed tomography (CT) scan (multi-detector or helical) of the abdomen and pelvis for staging with a CT chest or chest X-ray, and complete blood counts, renal and liver function tests. Endoscopic ultrasonography/ magnetic resonance imaging/positron emission tomography-CT is not recommended for all patients. For early stage disease (IA/B, N0), surgery alone is recommended. The need for adjuvant treatment would be guided by the histopathological analysis of the resected specimen. For locally advanced stage (IB, N(+) to IIIC), neoadjuvant chemotherapy may be considered to downstage the disease followed by surgery. This may be followed by adjuvant chemotherapy (as part of the peri-operative chemotherapy regimen). Patients with stage IV/metastatic disease must be assessed for chemotherapy versus best supportive care on an individual basis. Clinical examination including history and physical examination are recommended at each follow-up visit, with a yearly CT scan of the chest, abdomen, and pelvis. HER2 testing should be considered in patients with metastatic disease. 5-FU may be replaced with capecitabine if patients do not have gastric outlet obstruction. Cisplatin may be replaced with oxaliplatin in the regimens. |
format | Online Article Text |
id | pubmed-4264267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42642672014-12-23 Indian Council of Medical Research consensus document for the management of gastric cancer Shrikhande, Shailesh V. Sirohi, Bhawna Barreto, Savio G. Chacko, Raju T. Parikh, Purvish M. Pautu, Jeremy Arya, Supreeta Patil, Prachi Chilukuri, Srinivas C. Ganesh, B. Kaur, Tanvir Shukla, Deepak Rath, Goura Shankar Indian J Med Paediatr Oncol Position Paper The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India. Evaluation of a patient with newly diagnosed gastric cancer should include essential tests: A standard white light endoscopy with multiple biopsies from the tumor for confirmation of the diagnosis, a computed tomography (CT) scan (multi-detector or helical) of the abdomen and pelvis for staging with a CT chest or chest X-ray, and complete blood counts, renal and liver function tests. Endoscopic ultrasonography/ magnetic resonance imaging/positron emission tomography-CT is not recommended for all patients. For early stage disease (IA/B, N0), surgery alone is recommended. The need for adjuvant treatment would be guided by the histopathological analysis of the resected specimen. For locally advanced stage (IB, N(+) to IIIC), neoadjuvant chemotherapy may be considered to downstage the disease followed by surgery. This may be followed by adjuvant chemotherapy (as part of the peri-operative chemotherapy regimen). Patients with stage IV/metastatic disease must be assessed for chemotherapy versus best supportive care on an individual basis. Clinical examination including history and physical examination are recommended at each follow-up visit, with a yearly CT scan of the chest, abdomen, and pelvis. HER2 testing should be considered in patients with metastatic disease. 5-FU may be replaced with capecitabine if patients do not have gastric outlet obstruction. Cisplatin may be replaced with oxaliplatin in the regimens. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4264267/ /pubmed/25538398 http://dx.doi.org/10.4103/0971-5851.144970 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Position Paper Shrikhande, Shailesh V. Sirohi, Bhawna Barreto, Savio G. Chacko, Raju T. Parikh, Purvish M. Pautu, Jeremy Arya, Supreeta Patil, Prachi Chilukuri, Srinivas C. Ganesh, B. Kaur, Tanvir Shukla, Deepak Rath, Goura Shankar Indian Council of Medical Research consensus document for the management of gastric cancer |
title | Indian Council of Medical Research consensus document for the management of gastric cancer |
title_full | Indian Council of Medical Research consensus document for the management of gastric cancer |
title_fullStr | Indian Council of Medical Research consensus document for the management of gastric cancer |
title_full_unstemmed | Indian Council of Medical Research consensus document for the management of gastric cancer |
title_short | Indian Council of Medical Research consensus document for the management of gastric cancer |
title_sort | indian council of medical research consensus document for the management of gastric cancer |
topic | Position Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264267/ https://www.ncbi.nlm.nih.gov/pubmed/25538398 http://dx.doi.org/10.4103/0971-5851.144970 |
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