Combination of specific single chain antibody variable fragment and siRNA has a synergistic inhibitory effect on the propagation of avian influenza virus H5N1 in chicken cells

BACKGROUND: The avian influenza virus (AIV) causes frequent disease with high morbidity and mortality. RNA interference (RNAi) has been shown to provide an effective antiviral defense in animals, and several studies have focused on harnessing small interfering RNAs (siRNAs) to inhibit viral infectio...

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Detalles Bibliográficos
Autores principales: Wang, Shuang, Zhang, Peng, He, Fei, Wang, Ji-Gui, Sun, Jia-Zeng, Li, Zhi-Li, Yi, Bao, Xi, Ji, Mao, Ya-Ping, Hou, Qiang, Yuan, Dao-Li, Zhang, Zi-Ding, Liu, Wei-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264339/
https://www.ncbi.nlm.nih.gov/pubmed/25471220
http://dx.doi.org/10.1186/s12985-014-0208-x

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