Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

BACKGROUND: Male breast cancer (MBC) is still poorly understood with a large proportion arising in families with a history of breast cancer. Genomic studies have focused on germline determinants of MBC risk, with minimal knowledge of somatic changes in these cancers. METHODS: Using a TruSeq amplicon...

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Detalles Bibliográficos
Autores principales: Deb, S, Wong, S Q, Li, J, Do, H, Weiss, J, Byrne, D, Chakrabarti, A, Bosma, T, Fellowes, A, Dobrovic, A, Fox, S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264438/
https://www.ncbi.nlm.nih.gov/pubmed/25490678
http://dx.doi.org/10.1038/bjc.2014.511

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