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Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system
BACKGROUND: Metastatic outgrowth in breast cancer can occur years after a seeming cure. Existing model systems of dormancy are limited as they do not recapitulate human metastatic dormancy without exogenous manipulations and are unable to query early events of micrometastases. METHODS: Here, we desc...
Autores principales: | Wheeler, S E, Clark, A M, Taylor, D P, Young, C L, Pillai, V C, Stolz, D B, Venkataramanan, R, Lauffenburger, D, Griffith, L, Wells, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264444/ https://www.ncbi.nlm.nih.gov/pubmed/25314052 http://dx.doi.org/10.1038/bjc.2014.533 |
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