Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

Background: Controlled human malaria infection (CHMI) studies are a vital tool to accelerate vaccine and drug development. As CHMI trials are performed in a controlled environment, they allow unprecedented, detailed evaluation of parasite growth dynamics (PGD) and immunological responses. However, C...

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Detalles Bibliográficos
Autores principales: Hodgson, Susanne H., Juma, Elizabeth, Salim, Amina, Magiri, Charles, Kimani, Domtila, Njenga, Daniel, Muia, Alfred, Cole, Andrew O., Ogwang, Caroline, Awuondo, Ken, Lowe, Brett, Munene, Marianne, Billingsley, Peter F., James, Eric R., Gunasekera, Anusha, Sim, B. Kim L., Njuguna, Patricia, Rampling, Thomas W., Richman, Adam, Abebe, Yonas, Kamuyu, Gathoni, Muthui, Michelle, Elias, Sean C., Molyneux, Sassy, Gerry, Stephen, Macharia, Alex, Williams, Thomas N., Bull, Peter C., Hill, Adrian V. S., Osier, Faith H., Draper, Simon J., Bejon, Philip, Hoffman, Stephen L., Ogutu, Bernhards, Marsh, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264479/
https://www.ncbi.nlm.nih.gov/pubmed/25566206
http://dx.doi.org/10.3389/fmicb.2014.00686

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