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Influence of the rs1080985 Single Nucleotide Polymorphism of the CYP2D6 Gene and APOE Polymorphism on the Response to Donepezil Treatment in Patients with Alzheimer's Disease in China

BACKGROUND/AIM: Recent data have indicated that the rs1080985 single nucleotide polymorphism (SNP) of the cytochrome P450 (CYP) 2D6 and the common apolipoprotein E (APOE) gene may affect the response to donepezil in patients with Alzheimer's disease (AD). We investigated this association in Chi...

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Detalles Bibliográficos
Autores principales: Liu, Mengyuan, Zhang, Ying, Huo, Ya Ruth, Liu, Shuling, Liu, Shuai, Wang, Junwei, Wang, Change, Wang, Jinhuan, Ji, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264516/
https://www.ncbi.nlm.nih.gov/pubmed/25538729
http://dx.doi.org/10.1159/000367596