Cargando…

Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity

Neural progenitor cells (NPCs) derived from human pluripotent stem cells (hPSCs) are a multipotent cell population that is capable of nearly indefinite expansion and subsequent differentiation into the various neuronal and supporting cell types that comprise the CNS. However, current protocols for d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moya, Noel, Cutts, Josh, Gaasterland, Terry, Willert, Karl, Brafman, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264562/ https://www.ncbi.nlm.nih.gov/pubmed/25458891 http://dx.doi.org/10.1016/j.stemcr.2014.10.004

Ejemplares similares

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells
por: Kumar, Nathan, et al.
Publicado: (2015)

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells
por: Huggins, Ian J., et al.
Publicado: (2017)

Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells
por: Brafman, David A., et al.
Publicado: (2013)

FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision
por: Hackland, James O.S., et al.
Publicado: (2019)

BIG-TREE: Base-Edited Isogenic hPSC Line Generation Using a Transient Reporter for Editing Enrichment
por: Brookhouser, Nicholas, et al.
Publicado: (2020)

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes
por: Imaizumi, Kent, et al.
Publicado: (2015)

WNT5A Encodes Two Isoforms with Distinct Functions in Cancers
por: Bauer, Matthieu, et al.
Publicado: (2013)

Transfection of hPSC-Cardiomyocytes Using Viafect™ Transfection Reagent
por: Bodbin, Sara E., et al.
Publicado: (2020)

hPSC-derived organoids: models of human development and disease
por: Frum, Tristan, et al.
Publicado: (2020)

hPSC-derived lung organoids: Potential opportunities and challenges
por: Du, Xiaoli, et al.
Publicado: (2023)

Correction to: hPSC-derived organoids: models of human development and disease
por: Frum, Tristan, et al.
Publicado: (2020)

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
por: Heller, Sandra, et al.
Publicado: (2021)

Advances in hPSC expansion towards therapeutic entities: A review
por: Tannenbaum, Shelly E., et al.
Publicado: (2022)

Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies
por: Kim, Jung-Hyun, et al.
Publicado: (2022)

Dynamic regulation of GATA2 in fate determination in hematopoiesis: possible approach to hPSC-derived hematopoietic stem/progenitor cells
por: Zhou, Ya, et al.
Publicado: (2020)

Assessing Cell Competition in Human Pluripotent Stem Cell (hPSC) Cultures
por: Price, Christopher J., et al.
Publicado: (2022)

Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors
por: Blauwkamp, Timothy A., et al.
Publicado: (2012)

Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
por: Halloin, Caroline, et al.
Publicado: (2019)

Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
por: Halloin, Caroline, et al.
Publicado: (2019)

Engineering induction of singular neural rosette emergence within hPSC-derived tissues
por: Knight, Gavin T, et al.
Publicado: (2018)

The endothelium, a key actor in organ development and hPSC-derived organoid vascularization
por: Vargas-Valderrama, Alejandra, et al.
Publicado: (2020)

Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations
por: Kilpatrick, Savannah, et al.
Publicado: (2023)

Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation
por: Taga, Shiori, et al.
Publicado: (2023)

Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells
por: Fujimori, Koki, et al.
Publicado: (2017)

Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format
por: Mannhardt, Ingra, et al.
Publicado: (2020)

High-throughput 3D screening for differentiation of hPSC-derived cell therapy candidates
por: Muckom, Riya, et al.
Publicado: (2020)

Ultrasensitive and rapid quantification of rare tumorigenic stem cells in hPSC-derived cardiomyocyte populations
por: Wang, Zongjie, et al.
Publicado: (2020)

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease
por: Coccia, Elena, et al.
Publicado: (2021)

Comparative microelectrode array data of the functional development of hPSC-derived and rat neuronal networks
por: Kapucu, Fikret Emre, et al.
Publicado: (2022)

Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids
por: Rao, Kavitha S., et al.
Publicado: (2022)

Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential
por: Vattulainen, Meri, et al.
Publicado: (2019)

Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice
por: Sun, Jiaqi, et al.
Publicado: (2020)

The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
por: Poon, Ellen Ngar-Yun, et al.
Publicado: (2020)

Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation
por: Jo, Hye-Yeong, et al.
Publicado: (2020)

Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide
por: Li, Zongyi, et al.
Publicado: (2022)

An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection
por: Lang, Jianshe, et al.
Publicado: (2018)

Microscale grooves regulate maturation development of hPSC‐CMs by the transient receptor potential channels (TRP channels)
por: Liu, Taoyan, et al.
Publicado: (2021)

Sulfated Alginate Reduces Pericapsular Fibrotic Overgrowth on Encapsulated cGMP-Compliant hPSC-Hepatocytes in Mice
por: Syanda, Adam M., et al.
Publicado: (2022)

Bi-potential hPSC-derived Müllerian duct-like cells for full-thickness and functional endometrium regeneration
por: Gong, Lin, et al.
Publicado: (2022)

Transcriptomics of CD29(+)/CD44(+) cells isolated from hPSC retinal organoids reveals a single cell population with retinal progenitor and Müller glia characteristics
por: Eastlake, Karen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fgndhf75k5l6gjireo43log2lc