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Growth Rate Analysis and Efficient Experimental Design for Tumor Xenograft Studies

Human tumor xenograft studies are the primary means to evaluate the biological activity of anticancer agents in late-stage preclinical drug discovery. The variability in the growth rate of human tumors established in mice and the small sample sizes make rigorous statistical analysis critical. The mo...

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Detalles Bibliográficos
Autores principales: Hather, Gregory, Liu, Ray, Bandi, Syamala, Mettetal, Jerome, Manfredi, Mark, Shyu, Wen-Chyi, Donelan, Jill, Chakravarty, Arijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264612/
https://www.ncbi.nlm.nih.gov/pubmed/25574127
http://dx.doi.org/10.4137/CIN.S13974