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Growth Rate Analysis and Efficient Experimental Design for Tumor Xenograft Studies
Human tumor xenograft studies are the primary means to evaluate the biological activity of anticancer agents in late-stage preclinical drug discovery. The variability in the growth rate of human tumors established in mice and the small sample sizes make rigorous statistical analysis critical. The mo...
Autores principales: | Hather, Gregory, Liu, Ray, Bandi, Syamala, Mettetal, Jerome, Manfredi, Mark, Shyu, Wen-Chyi, Donelan, Jill, Chakravarty, Arijit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264612/ https://www.ncbi.nlm.nih.gov/pubmed/25574127 http://dx.doi.org/10.4137/CIN.S13974 |
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